pharm
Thursday, May 23, 2019
The intensity of passive diffusion of drug substances through the cell membrane is determined by
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degree of substance lipophilicity, concentration gradient
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Drug X produces maximal contraction of cardiac muscle in a manner similar to epinephrine (adrenaline). Drug X is considered to be a(n)
agonist
Two drugs act on the same tissue through independent receptors, resulting in effects in opposite directions. This is known as
physiologic antagonism
Lipophilic drugs penetrate the membrane at a speed proportional to the concentration gradient and the distribution coefficient (lipid/water) in the following way
simple diffusion
Idiosyncratic reaction of a drug is
unpredictable, inherent, qualitatively abnormal reaction to a drug
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