pharm
Sunday, June 9, 2019
A 16 –year –old girl suffering from seasonal rhinitis started a therapy with loratadine, a drug that binds to H1 histamine receptors. Which of the following terms best defines to the intrinsic ability of a drug to bind to a receptors
affinity
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Drug X produces maximal contraction of cardiac muscle in a manner similar to epinephrine (adrenaline). Drug X is considered to be a(n)
agonist
Two drugs act on the same tissue through independent receptors, resulting in effects in opposite directions. This is known as
physiologic antagonism
Lipophilic drugs penetrate the membrane at a speed proportional to the concentration gradient and the distribution coefficient (lipid/water) in the following way
simple diffusion
Idiosyncratic reaction of a drug is
unpredictable, inherent, qualitatively abnormal reaction to a drug
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